• greenbit@lemmy.zip
    1·
    1 month ago

    Definitely more enlightenment than the group average… that size of the crowd however

    • daannii@lemmy.worldOPEnglish
      0·
      1 month ago

      Lsd is often distributed and consumed via small paper squares called “tabs” that’s made on blotter paper. The paper is thick like cardstock. Sometimes with colorful psychedelic artwork printed on it.

      The lsd is diluted in a solution and the paper is soaked in the solution.

      The tiny microscopic lsd crystals deposit on the paper. The blotter paper is divided into 1cm squares. Correction. 5mm squares

      Lsd is neutralized by many chemicals , including chlorine (found in tap water) and stomach enzymes. It cannot be swallowed and still have an effect. Unless mixed with other compounds. This property was for dmt/ayuhasha and not lsd. Apologies. Chlorine can neutralize LSD and is found in tap water but I can’t find the resource for how much chlorine is in an average ml of tap water and how much is needed to neutralize 100ug LSD on a paper tab, right now, so I’ll retract that statement until I feel like digging more for the research on it.

      To take LSD, a person will place squares (typically one square is 1x 100ug dose) of the paper on the tounge or under it. And hold for about 5 -15 minutes. Some people take more than one. It can’t kill you. There is no overdose . But it can lead to accidents in high doses that can kill you. So it’s not risk free even if health risks are low.

      Also I said ug. Not mg. The lsd drug is very unique in that it has high potency at micrograms. Fentanyl is another drug that has that property . But it is rare.

      The lining of the mouth (mucus membranes) allows for easy transfer of the drug into the blood stream. That’s true for a lot of drugs actually.

      This is why lsd has such a unique drug delivery method though. It can’t be swallowed and it should be used in very small doses.

      Lsd is also very resistant to degredation. Oxygen, sunlight, and neutralizing chemicals like chlorine can degrade it. But if it’s stored properly it can last a very very long time. This is another rare property it has. Many other drugs degrade even when stored in air tight containers in dark and cool environments (like opiates).

      It’s also clear, tasteless, and no odor.

      I’m a perception researcher and , of course, this would be a drug on my radar. So I know quite a bit about it but I’m not a pharmacologist , I’m a cognitive researcher. I’ve given a lecture on psychedelics. It’s a fascinating topic.

      Also I’m generally interested in psycho-pharmacology because , well, it’s interesting.

      If you want to learn more interesting facts about LSD and other psychedelics, ask away.

      **Guy in picture has two tabs (squares of blotter paper) on his tongue and is wearing sunglasses because lsd dialates your pupils and makes your eyes sensitive to light.

      • BlasphemousTiefling@lemmy.ml
        0·
        1 month ago

        Honestly, damn. That sounds like a very interesting topic. If I wanted to learn more what resources would you recommend? (preferably textbooks/articles)

        • daannii@lemmy.worldOPEnglish
          0·
          1 month ago

          You know there isn’t much in a single location aside from Wikipedia.

          In textbooks I’ve come across , there is discussion of the pharmacology properties or a brief note about counter culture and general effects.

          There is limited research on the drug as it’s been black listed for almost 50 years and even now, it’s primarily only researched for terminally ill people/mental health. Only a handful of those studies exist and none use double blind controls so the science quality is poor.

          I myself am not convinced it has mental health benefits due to the way the drug works. It does however have strong suggestive effects meaning the drug itself promotes placebo/expectation effects.

          The lecture I put together for my class (perception and sensation ) pulled info from a wide range of resources.

          However there is one organization trying it’s best to do modern research and they have done some MRI studies. There was also a study on LSD and synesthesia which sheds a lot of light into the mechanisms. MAPS is the organization. https://maps.org/

          They have videos on YouTube with researchers discussing the research and studies they have done. But they mostly focus (last few years at least) on it’s use in mental health.

          The drug property information I know about is mostly pulled from old research from the 60s before the research bans. A lot was done on animals to understand dosage and half life. The cascade effects of how this drug works are still not really understood. We do know that the drug is similar in structure to serotonin. But there are still a lot of unknowns.

          Let me dig around for my resource links. I have a few interesting studies I found when preparing the lecture, including the synesthesia one, and I’ll organize it all and I’ll put a link up to a g drive with it.

          The lecture I did was 3 hrs long about hallucinations with a chunk dedicated to psychedelics. It did rely on other lecture materials to understand or otherwise id just put it up. (It was the final lecture for the class so it referred back multiple times to previous lessons). But maybe I can re-write it a bit. I’ve honestly been thinking of turning it into a video for a while because there are so few resources out there that review it more broadly. And a hell of a lot of misinformation about hallucinations and psychedelics.

          Basically this lecture was on hallucinations and the primary causes and how each of these causes relies on the same root changes in brain processing.

          For instance. You are driving on a country road at night. Vigilant to look for deer. Multiple times you were sure you saw an animal near the road but soon realized it was a fence post. Or an old glass bottle reflecting your headlamps. But for a split moment you did see an animal there before you corrected the perception.

          What ultimately caused that is what causes hallucinations in other situations. Like schizophrenia and drug use.

          So we circle around neuroscience, psychiatry, physiology, and pharmacology. As well as cultural impacts influencing the experience of hallucinations or psychedelics.

          This is getting long. Apologies. The lecture is 3 hrs and relies on many other hours of information. It’s a big topic.

    • DaGeek247@fedia.io
      1·
      1 month ago

      Well, he has two tabs, so more like two spiritual experiences at the same time instead.